Circulating stem cells, HIF-1, and SDF-1 in septic abdominal surgical patients: randomized controlled study protocol

Circulating stem cells, HIF-1, and SDF-1 in septic abdominal surgical patients: randomized controlled study protocol

Abstract Background Sepsis caused by complicated intra-abdominal infection is associated with high mortality. Loss of endothelial barrier integrity, inflammation, and impaired cellular oxygen have been shown to be primary contributors to sepsis. To date, little is known regarding the pathway for the...

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Bibliographic Details
Main Authors: Antonella Cotoia, Lucia Mirabella, Sabrina Altamura, Rachele Villani, Flavia Marchese, Giuseppe Ferrara, Karim Mariano, Tullo Livio, Gilda Cinnella
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Trials
Subjects:
Stem cells
Major abdominal surgery
Sepsis
Septic shock
Stromal cell-derived factor 1a
Hypoxia inducible factor 1
Online Access:http://link.springer.com/article/10.1186/s13063-018-2556-0

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http://link.springer.com/article/10.1186/s13063-018-2556-0

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