Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts

Keloid is a disorder of fibroproliferative diseases that occurs in wounds, characterized by an exaggerated response to injury. The key factor responsible for the disease process has not been identified. This study sought to elucidate the role of β-catenin in the regulation of keloid phenotypes and s...

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Bibliographic Details
Main Authors: Yumei Cai, Shize Zhu, Weiqun Yang, Mingmeng Pan, Chaoyang Wang, Wenyi Wu
Format: Article
Language:English
Published: IOS Press 2017-06-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317707423