HTR2B and SLC5A3 Are Specific Markers in Age-Related Osteoarthritis and Involved in Apoptosis and Inflammation of Osteoarthritis Synovial Cells

HTR2B and SLC5A3 Are Specific Markers in Age-Related Osteoarthritis and Involved in Apoptosis and Inflammation of Osteoarthritis Synovial Cells

Objective: Osteoarthritis (OA) is a heterogeneous age-related disease, which is badly difficult to cure due to its complex regulatory networks of pathogenesis. This study explored OA-specific genes in synovial tissues and validated their roles on apoptosis and inflammation of OA synovial cells.Metho...

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Bibliographic Details
Main Authors: Xin Lu, Yu Fan, Mingxia Li, Xiao Chang, Jun Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
osteoarthritis
synovial tissues
weighted correlation network analysis
HTR2B
SLC5A3
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.691602/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.691602/full

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