Tumor Mutation Burden Predicts Relapse in Papillary Thyroid Carcinoma With Changes in Genes and Immune Microenvironment

Tumor Mutation Burden Predicts Relapse in Papillary Thyroid Carcinoma With Changes in Genes and Immune Microenvironment

BackgroundThe risk factors of papillary thyroid carcinoma (PTC) recurrence are meaningful for patients and clinicians. Tumor mutation burden (TMB) has been a biomarker for the effectiveness of immune checkpoint inhibitor (ICI) and prognosis in cancer. However, the role of TMB and its latent signific...

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Bibliographic Details
Main Authors: Mengli Guo, Zhen Chen, Yayi Li, Sijin Li, Fei Shen, Xiaoxiong Gan, Jianhua Feng, Wensong Cai, Qingzhi Liu, Bo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Endocrinology
Subjects:
papillary thyroid carcinoma (PTC)
prognosis
The Cancer Genome Atlas (TCGA)
tumor mutation burden (TMB)
immune infiltrate
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.674616/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.674616/full

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