A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase.

A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase.

BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...

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Main Authors: Mutsuki Amano, Yuta Tsumura, Kentaro Taki, Hidenori Harada, Kazutaka Mori, Tomoki Nishioka, Katsuhiro Kato, Takeshi Suzuki, Yosuke Nishioka, Akihiro Iwamatsu, Kozo Kaibuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806833?pdf=render

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http://europepmc.org/articles/PMC2806833?pdf=render

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