Role of Peroxiredoxin III in the Pathogenesis of Pre-eclampsia as Evidenced in Mice

As a member of peroxiredoxin (Prx) family, PrxIII has been demonstrated to play an important role in scavenging intracellular reactive oxygen species (ROS). Since PrxIII knockout mice exhibited oxidative stress in placentas resembling pathophysiologic changes in placentas of human pre-eclampsia, we...

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Bibliographic Details
Main Authors: Lianqin Li, Masuo Obinata, Katsuyoshi Hori
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.4161/oxim.3.1.10094