Mosaic VSGs and the scale of Trypanosoma brucei antigenic variation.

A main determinant of prolonged Trypanosoma brucei infection and transmission and success of the parasite is the interplay between host acquired immunity and antigenic variation of the parasite variant surface glycoprotein (VSG) coat. About 0.1% of trypanosome divisions produce a switch to a differe...

Full description

Bibliographic Details
Main Authors: James P J Hall, Huanhuan Wang, J David Barry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23853603/?tool=EBI