Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection

An exacerbated immune response is one of the main causes of influenza-induced lung damage during infection. The molecular mechanisms regulating the fate of the initial immune response to infection, either as a protective response or as detrimental immunopathology, are not well understood. The purine...

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Bibliographic Details
Main Authors: Victor H. Leyva-Grado, Megan E. Ermler, Michael Schotsaert, Ma G. Gonzalez, Virginia Gillespie, Jean K. Lim, Adolfo García-Sastre, Christine A. Biron
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00229-17