Adiponectin-Transfected Endothelial Progenitor Cells Have Protective Effects After 2-Hour Middle-Cerebral Artery Occlusion in Rats With Type 2 Diabetes Mellitus

Adiponectin-Transfected Endothelial Progenitor Cells Have Protective Effects After 2-Hour Middle-Cerebral Artery Occlusion in Rats With Type 2 Diabetes Mellitus

Objectives: This present study aimed to examine the effects of adiponectin-transfected endothelial progenitor cells (LV-APN-EPCs) on cerebral ischemia–reperfusion injury in rats with type 2 diabetes mellitus (T2DM) and to explore the underlying mechanisms.Methods: Seventy male Sprague–Dawley rats wi...

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Bibliographic Details
Main Authors: Meiyao Wang, Yan Li, Renwei Zhang, Shuaimei Zhang, Hongliang Feng, Zhaohong Kong, Nadire Aiziretiaili, Zhengjin Luo, Qi Cai, Yan Hong, Yumin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neurology
Subjects:
type 2 diabetes mellitus
acute ischemic stroke
adiponectin-transfected endothelial progenitor cell
angiogenesis
protective effects
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.630681/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.630681/full

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