Chloroquine Urea Derivatives: Synthesis and Antitumor Activity in Vitro

In the current paper, we describe the design, synthesis and antiproliferative screening of novel chloroquine derivatives with a quinoline core linked to a hydroxy or halogen amine through a flexible aminobutyl chain and urea spacer. Synthetic pathway leading to chloroquine urea derivatives 4-10 incl...

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Bibliographic Details
Main Authors: Pavić Kristina, Rajić Zrinka, Mlinarić Zvonimir, Uzelac Lidija, Kralj Marijeta, Zorc Branka
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2018-0039