Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy

Nicotine Reduces Human Brain Microvascular Endothelial Cell Response to Escherichia coli K1 Infection by Inhibiting Autophagy

Studies have shown that exposure to environmental tobacco smoke can increase the risk of bacterial meningitis, and nicotine is the core component of environmental tobacco smoke. Autophagy is an important way for host cells to eliminate invasive pathogens and resist infection. Escherichia coli K1 str...

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Bibliographic Details
Main Authors: Chao Wu, Mengzhen Yang, Rui Liu, Hanyang Hu, Lulu Ji, Xiaoli Zhang, Shenghe Huang, Lin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
autophagy
human brain microvascular endothelial cells
nicotine
Escherichia coli
neonatal meningitis
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00484/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00484/full

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