The immunogenetics of multiple sclerosis. The frequency of HLA-alleles class 1 and 2 is lower in Southern Brazil than in the European population

ABSTRACT Objective To study the HLA of class 1and 2 in a multiple sclerosis (MS) population to verify the susceptibility for the disease in the Southern Brazil. Methods We analyzed patients with MS and controls, by direct sequencing of the genes related to HLA DRB1, DQB1, DPB1, A, B and C allele...

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Bibliographic Details
Main Authors: Lineu Cesar Werneck, Paulo José Lorenzoni, Raquel Cristina Arndt, Cláudia Suemi Kamoi Kay, Rosana Herminia Scola
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2016-08-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000800607&lng=en&tlng=en