The Genomic Pattern of tDNA Operon Expression in E. coli.
In fast-growing microorganisms, a tRNA concentration profile enriched in major isoacceptors selects for the biased usage of cognate codons. This optimizes translational rate for the least mass invested in the translational apparatus. Such translational streamlining is thought to be growth-regulated,...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2005-06-01
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Series: | PLoS Computational Biology |
Online Access: | http://dx.doi.org/10.1371/journal.pcbi.0010012 |