Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge

Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge

Alpha-1 antitrypsin, a small glycoprotein clade A serpine serine protease inhibitor of neutrophil elastase has been shown to increase in humans following bacterial and viral infection. However, we report here significant reduction of this major inhibitor of elastase in plasma of F. tularensis LVS a...

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Bibliographic Details
Main Authors: James Patrick Chambers, Jieh-Juen eYu, Madhulika eJupelli, Susan T Weintraub, Jose L Lopez-Ribot, James J. Valdes, Bernard P. Arulanandam
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Francisella
Plasma
Neutrophil
antiprotease
antitrypsin
elastase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00020/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00020/full

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