The Cytotoxicity of RNase-Derived Peptides

The Cytotoxicity of RNase-Derived Peptides

Bacterial ribonuclease binase exhibits a cytotoxic effect on tumor cells possessing certain oncogenes. The aim of this study was to identify the structural parts of the binase molecule that exert cytotoxicity. Out of five designed peptides, the peptides representing the binase regions 21–50 and 74–9...

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Bibliographic Details
Main Authors: Vera Ulyanova, Elena Dudkina, Alsu Nadyrova, Vladimir Kalashnikov, Yulia Surchenko, Olga Ilinskaya
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
anticancer peptides
ribonuclease (RNase)
binase
cytotoxicity
EGF
epidermal growth factor EGFR
Online Access:https://www.mdpi.com/2218-273X/11/1/16

Internet

https://www.mdpi.com/2218-273X/11/1/16

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