Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections.

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections.

It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1β and the T cell maturation marker CD27 within CMVpp65-specific CD4(+) and CD8(+) T cells in relation to age, HIV and acti...

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Bibliographic Details
Main Authors: Damien Portevin, Félicien Moukambi, Maxmillian Mpina, Asli Bauer, Frederick Haraka, Mkunde Chachage, Philipp Metzger, Elmar Saathoff, Petra Clowes, Nyanda E Ntinginya, Andrea Rachow, Michael Hoelscher, Klaus Reither, Claudia A Daubenberger, Christof Geldmacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126716

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https://doi.org/10.1371/journal.pone.0126716

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