Design, Synthesis and DFT/DNP Modeling Study of New 2-Amino-5-arylazothiazole Derivatives as Potential Antibacterial Agents

A new series of 2-amino-5-arylazothiazole derivatives has been designed and synthesized in 61–78% yields and screened as potential antibacterial drug candidates against the Gram negative bacterium Escherichia coli. The geometry of the title compounds were being studied using the Material Studio pack...

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Bibliographic Details
Main Author: Sraa Abu-Melha
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
DFT
Online Access:http://www.mdpi.com/1420-3049/23/2/434