The effect of alcohol on recombinant proteins derived from mammalian adenylyl cyclase
The cyclic AMP (cAMP) signaling pathway is implicated in the development of alcohol use disorder. Previous studies have demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform specific manner; AC7 is most enhanced by ethanol, and regions responsible for enhancement by...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-07-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580816303715 |