Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

<p>Abstract</p> <p>Background</p> <p>Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, actively transcribed genes ha...

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Bibliographic Details
Main Authors: Silver Pamela A, Garakani Arman M, Drubin David A
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/7/19