A Bayesian mixed modeling approach for estimating heritability

Abstract Background A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate genome-wide patterns of DNA methylation heritability (h 2 ), which are currently n...

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Bibliographic Details
Main Authors: Haakon E. Nustad, Christian M. Page, Andrew H. Reiner, Manuela Zucknick, Marissa LeBlanc
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0131-z