MEX3C interacts with adaptor-related protein complex 2 and involves in miR-451a exosomal sorting.

Some RNA species, especially microRNAs, are non-randomly sorted into exosomes, but how selectivity of RNA exosomal sorting is achieved is unknown. We found that all three variants of RNA-binding ubiquitin E3 ligase (MEX3C)-MEX3C-1, MEX3C-2, and MEX3C-3 -interact with adaptor-related protein complex...

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Bibliographic Details
Main Authors: Pin Lu, Huanhuan Li, Ning Li, Ravi N Singh, Colin E Bishop, Xiangxian Chen, Baisong Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5628917?pdf=render