Koumine Attenuates Lipopolysaccaride-Stimulated Inflammation in RAW264.7 Macrophages, Coincidentally Associated with Inhibition of NF-κB, ERK and p38 Pathways

Koumine Attenuates Lipopolysaccaride-Stimulated Inflammation in RAW264.7 Macrophages, Coincidentally Associated with Inhibition of NF-κB, ERK and p38 Pathways

Medicinal herbal plants have been commonly used for intervention of different diseases and health enhancement worldwide. Koumine, an alkaloid monomer found abundantly in Gelsemium plants, can be effectively used as an anti-inflammatory medication. In this study, the mechanisms associated with the pr...

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Bibliographic Details
Main Authors: Zhihang Yuan, Froilan Bernard Matias, Jing Wu, Zengenni Liang, Zhiliang Sun
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:International Journal of Molecular Sciences
Subjects:
koumine
inflammation
LPS
NO
iNOS
NF-κB
RAW264.7 macrophages
Online Access:http://www.mdpi.com/1422-0067/17/3/430

Internet

http://www.mdpi.com/1422-0067/17/3/430

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