Uncoupling of T Cell Receptor Zeta Chain Function during the Induction of Anergy by the Superantigen, Staphylococcal Enterotoxin A

Uncoupling of T Cell Receptor Zeta Chain Function during the Induction of Anergy by the Superantigen, Staphylococcal Enterotoxin A

Staphylococcus aureus enterotoxins have immunomodulatory properties. In this study, we show that Staphylococcal enterotoxin A (SEA) induces a strong proliferative response in a murine T cell clone independent of MHC class II bearing cells. SEA stimulation also induces a state of hypo-responsiveness...

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Bibliographic Details
Main Authors: William D. Cornwell, Thomas J. Rogers
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Toxins
Subjects:
superantigen
Staphylococcus aureus
SEA
anergy
zeta chain
enterotoxin
Online Access:http://www.mdpi.com/2072-6651/2/7/1704/

Internet

http://www.mdpi.com/2072-6651/2/7/1704/

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