ALK immunohistochemistry is highly sensitive and specific for the detection of ALK translocated lung adenocarcinomas: lessons from an audit of lung cancer molecular testing

Background The approval of novel targeted treatments for epidermal growth factor receptor (EGFR)-positive and anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer has led to the increased requirement for mutation testing. Results We report our experience of ALK testing with immun...

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Bibliographic Details
Main Authors: YC Kheng, K Walsh, L Williams, WA Wallace, DJ Harrison, A Oniscu
Format: Article
Language:English
Published: Royal College of Physicians of Edinburgh 2018-03-01
Series:The Journal of the Royal College of Physicians of Edinburgh
Subjects:
ALK
Online Access:https://www.rcpe.ac.uk/sites/default/files/jrcpe_48_1_oniscu.pdf