Natural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice

Natural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice

Shiga toxin-producing Escherichia coli (STEC) is a leading cause of childhood renal disease He-molytic Uremic Syndrome (HUS). The involvement of renal cytokines and chemokines is sus-pected to play a critical role in disease progression. In current article, we tested the hypothesis that NKT cells...

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Bibliographic Details
Main Authors: Fumiko eObata, Priyanka B Subrahmanyam, Aimee E Vozenilek, Lauren M Hippler, Tynae eJeffers, Methinee eTongsuk, Irina eTiper, Progyaparamita eSaha, Dakshina M Jandhyala, Glynis L Kolling, Olga eLatinovic, Tonya J Webb
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Microbiology
Subjects:
Cytokines
Escherichia coli
Shiga Toxin
mouse models
Hemolytic uremic syndrome
Single molecule imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00262/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00262/full

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