Statistical characterization of therapeutic protein modifications

Statistical characterization of therapeutic protein modifications

Abstract Peptide mapping with liquid chromatography–tandem mass spectrometry (LC-MS/MS) is an important analytical method for characterization of post-translational and chemical modifications in therapeutic proteins. Despite its importance, there is currently no consensus on the statistical analysis...

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Bibliographic Details
Main Authors: Tsung-Heng Tsai, Zhiqi Hao, Qiuting Hong, Benjamin Moore, Cinzia Stella, Jeffrey H. Zhang, Yan Chen, Michael Kim, Theo Koulis, Gregory A. Ryslik, Erik Verschueren, Fred Jacobson, William E. Haskins, Olga Vitek
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08333-y

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https://doi.org/10.1038/s41598-017-08333-y

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