Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin

Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin

Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the skin remain largely unknown. We investigated the signal transduction pathway and epigenetic regulatory mechanisms underlying cellular inflammation induced by PM with a diameter of ≤ 2.5 (PM2.5) in vitro an...

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Bibliographic Details
Main Authors: Yea Seong Ryu, Kyoung Ah Kang, Mei Jing Piao, Mee Jung Ahn, Joo Mi Yi, Young-Min Hyun, Seo Hyeong Kim, Min Kyung Ko, Chang Ook Park, Jin Won Hyun
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718309522

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http://www.sciencedirect.com/science/article/pii/S2213231718309522

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