The Biological Functions and Clinical Applications of Integrins in Cancers

The Biological Functions and Clinical Applications of Integrins in Cancers

Integrins are the adhesion molecules and receptors of extracellular matrix (ECM). They mediate the interactions between cells-cells and cells-ECM. The crosstalk between cancer cells and their microenvironment triggers a variety of critical signaling cues and promotes the malignant phenotype of cance...

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Bibliographic Details
Main Authors: Chao-yue Su, Jing-quan Li, Ling-ling Zhang, Hui Wang, Feng-hua Wang, Yi-wen Tao, Yu-qing Wang, Qiao-ru Guo, Jia-jun Li, Yun Liu, Yan-yan Yan, Jian-ye Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
integrins
cancer metastasis
drug resistance
stemness
extracellular matrix
therapeutic targeting
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.579068/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.579068/full

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