Treatment Of Sunitinib-Induced Hypertension In Solid Tumors By Nitric Oxid Donors

Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) are overexpressed in the majority of renal cell carcinomas (RCC). This characteristic has supported the rationale of targeting VEGF-driven tumour vascularization, especially in clear cell RCC. VEGF-inhibiting strategies include the u...

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Bibliographic Details
Main Authors: Luís A. Leon, Luís M. Antón-Aparicio
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715001470