Generation of Mesenchymal Stromal Cells with Low Immunogenicity from Human PBMC-Derived β2 Microglobulin Knockout Induced Pluripotent Stem Cells
Mesenchymal stromal cells (MSCs) are viewed as immune-privileged cells and have been broadly applied in allogeneic adoptive cell transfer for regenerative medicine or immune-suppressing purpose. However, the surface expression of human leukocyte antigen (HLA) class I molecules on MSCs could still po...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-11-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/0963689720965529 |