Generation of Mesenchymal Stromal Cells with Low Immunogenicity from Human PBMC-Derived β2 Microglobulin Knockout Induced Pluripotent Stem Cells

Mesenchymal stromal cells (MSCs) are viewed as immune-privileged cells and have been broadly applied in allogeneic adoptive cell transfer for regenerative medicine or immune-suppressing purpose. However, the surface expression of human leukocyte antigen (HLA) class I molecules on MSCs could still po...

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Bibliographic Details
Main Authors: Shijun Zha, Johan Chin-Kang Tay, Sumin Zhu, Zhendong Li, Zhicheng Du, Shu Wang
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720965529