Placental chemokine compartmentalisation: A novel mammalian molecular control mechanism.

Atypical chemokine receptor 2 (ACKR2) is a chemokine-scavenging receptor. ACKR2-/-embryos display a reduction in size of a novel, to our knowledge, embryonic skin macrophage population referred to as 'intermediate' cells. CC chemokine receptor 2 (CCR2)-/-embryos display an identical phenot...

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Bibliographic Details
Main Authors: Kit Ming Lee, Gillian J Wilson, Marieke Pingen, Ayumi Fukuoka, Christopher A H Hansell, Robin Bartolini, Laura Medina-Ruiz, Gerard J Graham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000287