A Humanized Mouse Model Generated Using Surplus Neonatal Tissue

A Humanized Mouse Model Generated Using Surplus Neonatal Tissue

Summary: Here, we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus and umbilical cord blood hematopoietic stem cells (HSCs). Conventional humanized mouse models are made by engrafting human fetal thymus and HSCs into immunocompromi...

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Bibliographic Details
Main Authors: Matthew E. Brown, Ying Zhou, Brian E. McIntosh, Ian G. Norman, Hannah E. Lou, Mitch Biermann, Jeremy A. Sullivan, Timothy J. Kamp, James A. Thomson, Petros V. Anagnostopoulos, William J. Burlingham
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118301024

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http://www.sciencedirect.com/science/article/pii/S2213671118301024

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