Scaffold-Dependent Mechanical and Architectural Cues Guide Osteochondral Defect Healing in silico

Osteochondral defects in joints require surgical intervention to relieve pain and restore function. However, no current treatment enables a complete reconstitution of the articular surface. It is known that both mechanical and biological factors play a key role on osteochondral defect healing, howev...

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Bibliographic Details
Main Authors: Martina Tortorici, Ansgar Petersen, Klara Ehrhart, Georg N. Duda, Sara Checa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.642217/full