Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients.

Monocarboxylate transporter 4 (MCT4) is a cell membrane transporter of lactate. Recent studies have shown that MCT4 is over-expressed in various cancers; however, its role in cancer maintenance and aggressiveness has not been fully demonstrated. This study investigated the role of MCT4 in oral squam...

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Bibliographic Details
Main Authors: Jiang Zhu, Yu-Nong Wu, Wei Zhang, Xiao-Min Zhang, Xu Ding, Huai-Qi Li, Meiyu Geng, Zuo-Quan Xie, He-Ming Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3907573?pdf=render