Bri2 BRICHOS chaperone rescues impaired fast-spiking interneuron behavior and neuronal network dynamics in an AD mouse model in vitro

Bri2 BRICHOS chaperone rescues impaired fast-spiking interneuron behavior and neuronal network dynamics in an AD mouse model in vitro

Synchronized and properly balanced electrical activity of neurons is the basis for the brain's ability to process information, to learn, and to remember. In Alzheimer's disease (AD), which causes cognitive decline in patients, this synchronization and balance is disturbed by the accumulati...

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Bibliographic Details
Main Authors: Yuniesky Andrade-Talavera, Gefei Chen, Firoz Roshan Kurudenkandy, Jan Johansson, André Fisahn
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Gamma oscillations
Fast-spiking interneurons
hippocampus
Bri2 BRICHOS chaperone
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002631

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http://www.sciencedirect.com/science/article/pii/S0969996121002631

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