HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

Abstract Background Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could be detected in these patients in liquid biopsy and in cancer cells....

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Bibliographic Details
Main Authors: Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner, Janusz Milanowski
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Gastroenterology
Subjects:
Gastric cancer
Esophagogastric cancer
HER2 copy number
Liquid biopsy
Online Access:http://link.springer.com/article/10.1186/s12876-020-01531-5

Internet

http://link.springer.com/article/10.1186/s12876-020-01531-5

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