Mycotoxins’ Activity at Toxic and Sub-Toxic Concentrations: Differential Cytotoxic and Genotoxic Effects of Single and Combined Administration of Sterigmatocystin, Ochratoxin A and Citrinin on the Hepatocellular Cancer Cell Line Hep3B

Mycotoxins’ Activity at Toxic and Sub-Toxic Concentrations: Differential Cytotoxic and Genotoxic Effects of Single and Combined Administration of Sterigmatocystin, Ochratoxin A and Citrinin on the Hepatocellular Cancer Cell Line Hep3B

Food safety organizations indicate the likelihood of constant human and animal exposure to mycotoxin mixtures as a possible negative public health impact. Risk assessment demonstrates that certain mycotoxins of Aspergillus and Penicillium spp. are toxic and hold a significant genotoxic efficacy at n...

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Bibliographic Details
Main Authors: Nikolia Αnninou, Ekaterini Chatzaki, Fotini Papachristou, Μichail Pitiakoudis, Constantinos Simopoulos
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:International Journal of Environmental Research and Public Health
Subjects:
sterigmatocystin
ochratoxin A
citrinin
metabolic activity
genotoxicity
cytostaticity
cytotoxicity
picoMolar concentrations
Online Access:http://www.mdpi.com/1660-4601/11/2/1855

Internet

http://www.mdpi.com/1660-4601/11/2/1855

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