Using the R Package Spatstat to Assess Inhibitory Effects of Microregional Hypoxia on the Infiltration of Cancers of the Head and Neck Region by Cytotoxic T Lymphocytes

Using the R Package Spatstat to Assess Inhibitory Effects of Microregional Hypoxia on the Infiltration of Cancers of the Head and Neck Region by Cytotoxic T Lymphocytes

(1) Background: The immune system has physiological antitumor activity, which is partially mediated by cytotoxic T lymphocytes (CTL). Tumor hypoxia, which is highly prevalent in cancers of the head and neck region, has been hypothesized to inhibit the infiltration of tumors by CTL. In situ data vali...

Full description

Bibliographic Details
Main Authors: Justus Kaufmann, Christophe A. N. Biscio, Peter Bankhead, Stefanie Zimmer, Heinz Schmidberger, Ege Rubak, Arnulf Mayer
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
spatial analysis
open-source
R
hypoxia
cancer immune evasion
multichannel immunofluorescence
Online Access:https://www.mdpi.com/2072-6694/13/8/1924

Internet

https://www.mdpi.com/2072-6694/13/8/1924

Similar Items