Staphylococcus aureus Sortase A-Mediated Incorporation of Peptides: Effect of Peptide Modification on Incorporation.

The endogenous Staphylococcus aureus sortase A (SrtA) transpeptidase covalently anchors cell wall-anchored (CWA) proteins equipped with a specific recognition motif (LPXTG) into the peptidoglycan layer of the staphylococcal cell wall. Previous in situ experiments have shown that SrtA is also able to...

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Bibliographic Details
Main Authors: Silvie Hansenová Maňásková, Kamran Nazmi, Wim van 't Hof, Alex van Belkum, Nathaniel I Martin, Floris J Bikker, Willem J B van Wamel, Enno C I Veerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4723074?pdf=render