Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging.

Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging.

Alzheimer's disease (AD) is a complex neurodegenerative disorder that diverges from the process of normal brain aging by unknown mechanisms. We analyzed the global structure of age- and disease-dependent gene expression patterns in three regions from more than 600 brains. Gene expression variat...

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Bibliographic Details
Main Authors: Alexei A Podtelezhnikov, Keith Q Tanis, Michael Nebozhyn, William J Ray, David J Stone, Andrey P Loboda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247273?pdf=render

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http://europepmc.org/articles/PMC3247273?pdf=render

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