Suprachiasmatic lesions restore object recognition in down syndrome model mice
The Ts65Dn mouse is a well-studied model of trisomy 21, Down syndrome. This mouse strain has severe learning disability as measured by several rodent learning tests that depend on hippocampal spatial memory function. Hippocampal long-term potentiation (LTP) is deficient in these mice. Short-term dai...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-05-01
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| Series: | Neurobiology of Sleep and Circadian Rhythms |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451994420300018 |