In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFα impact of ω-3 versus ω-6 fatty acids

In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFα impact of ω-3 versus ω-6 fatty acids

Severe endothelial abnormalities are a prominent feature in sepsis with cytokines such as tumor necrosis factor (TNF)α being implicated in the pathogenesis. As mimic to inflammation, human umbilical vascular endothelial cells (HUVEC) were incubated with TNFα for 22 h, in the absence or presence of t...

Full description

Bibliographic Details
Main Authors: Konstantin Mayer, Reinhold Schmidt, Marion Muhly-Reinholz, Tina Bögeholz, Stephanie Gokorsch, Friedrich Grimminger, Werner Seeger
Format: Article
Language:English
Published: Elsevier 2002-06-01
Series:Journal of Lipid Research
Subjects:
arachidonic acid
eicosapentaenoic acid
mead acid
phosphatidylinositol
phosphatidylcholine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520304697

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520304697

Similar Items