Nrf2 in cancers: A double‐edged sword
Abstract The Nrf2/Keap1 pathway is an important signaling cascade responsible for the resistance of oxidative damage induced by exogenous chemicals. It maintains the redox homeostasis, exerts anti‐inflammation and anticancer activity by regulating its multiple downstream cytoprotective genes, thereb...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-05-01
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Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.2101 |