Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells.

Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells.

Aged garlic extract (AGE) is widely used as a dietary supplement, and is claimed to promote human health through anti-oxidant/anti-inflammatory activities with hypolipidemic, antiplatelet and neuroprotective effects. Prior studies of AGE have mainly focused on its organosulfur compounds, with little...

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Bibliographic Details
Main Authors: Hui Zhou, Zhe Qu, Valeri V Mossine, Dineo L Nknolise, Jilong Li, Zhenzhou Chen, Jianlin Cheng, C Michael Greenlief, Thomas P Mawhinney, Paula N Brown, Kevin L Fritsche, Mark Hannink, Dennis B Lubahn, Grace Y Sun, Zezong Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4242640?pdf=render

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http://europepmc.org/articles/PMC4242640?pdf=render

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