Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling

Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling

<p>Abstract</p> <p>Background</p> <p>Interferons (IFNs) are potent antiviral cytokines capable of reprogramming the macrophage phenotype through the induction of interferon-stimulated genes (ISGs). Here we have used targeted RNA interference to suppress the expression o...

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Bibliographic Details
Main Authors: Craigon Marie, Storm Petter, Forster Thorsten, Page David, Sing Garwin, Raza Sobia, Lacaze Paul, Awad Tarif, Ghazal Peter, Freeman Tom C
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/372

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http://www.biomedcentral.com/1471-2164/10/372

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