Renal Protective Effects of Low Molecular Weight of Inonotus obliquus Polysaccharide (LIOP) on HFD/STZ-Induced Nephropathy in Mice

Renal Protective Effects of Low Molecular Weight of Inonotus obliquus Polysaccharide (LIOP) on HFD/STZ-Induced Nephropathy in Mice

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in diabetes mellitus. Oxidative stress, insulin resistance and pro-inflammatory cytokines have been shown to play an important role in pathogeneses of renal damage on type 2 diabetes mellitus (DM). Inonotus obliquus (IO) is a...

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Bibliographic Details
Main Authors: Yen-Jung Chou, Wei-Chih Kan, Chieh-Min Chang, Yi-Jen Peng, Hsien-Yi Wang, Wen-Chun Yu, Yu-Hsuan Cheng, Yu-Rou Jhang, Hsia-Wei Liu, Jiunn-Jye Chuu
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic nephropathy
Inonotus obliquus
polysaccharides
renal fibrosis
advanced glycation end products (AGE)
NF-κB
TGF-β
Online Access:http://www.mdpi.com/1422-0067/17/9/1535

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http://www.mdpi.com/1422-0067/17/9/1535

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