Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development

Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development

During palatogenesis, the palatal shelves first grow vertically on either side of the tongue before changing their direction of growth to horizontal. The extracellular matrix (ECM) plays an important role in these dynamic changes in palatal shelf morphology. Tenascin-C (TNC) is an ECM glycoprotein t...

Full description

Bibliographic Details
Main Authors: Shirabe Ohki, Kyoko Oka, Kayoko Ogata, Shigeru Okuhara, Mihoko Rikitake, Masako Toda-Nakamura, Shougo Tamura, Masao Ozaki, Sachiko Iseki, Takayoshi Sakai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
soft palate
palatogenesis
tumor growth factor-beta
tenascin-C
sonic hedgehog
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00532/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00532/full

Similar Items