Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C

Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C

<p>Inosine triphosphatase (ITPA) single nucleotide polymorphisms (SNPs) are strongly associated with protection against ribavirin (RBV)-induced anaemia in European, American and Asian patients; however, there is a paucity of data for Brazilian patients. The aim of this study was to evaluate th...

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Bibliographic Details
Main Authors: Nathália Delvaux, Vanessa Duarte da Costa, Maristella Matos da Costa, Livia Melo Villar, Henrique Sérgio Moraes Coelho, Eliane Bordalo Cathalá Esberard, Priscila Pollo Flores, Carlos Eduardo Brandão-Mello, Cristiane Alves Villela-Nogueira, Adilson José de Almeida, Elisabeth Lampe
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2015-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
ITPA
hepatitis C
ribavirin
anaemia
Brazil
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000500636&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000500636&lng=en&tlng=en

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