Plasmodium falciparum field isolates from South America use an atypical red blood cell invasion pathway associated with invasion ligand polymorphisms.

Studies of Plasmodium falciparum invasion pathways in field isolates have been limited. Red blood cell (RBC) invasion is a complex process involving two invasion protein families; Erythrocyte Binding-Like (EBL) and the Reticulocyte Binding-Like (PfRh) proteins, which are polymorphic and not fully ch...

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Bibliographic Details
Main Authors: Mary Lopez-Perez, Elizabeth Villasis, Ricardo L D Machado, Marinete M Póvoa, Joseph M Vinetz, Silvia Blair, Dionicia Gamboa, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485327?pdf=render