Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats?

Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats?

Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like behaviour in the Wistar Albino Glaxo from Rijswi...

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Bibliographic Details
Main Authors: Slavianka Moyanova, Antonio De Fusco, Ines Santolini, Roberta Celli, Domenico Bucci, Federica Mastroiacovo, Giuseppe Battaglia, Ferdinando Nicoletti, Jane Tchekalarova
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
absence seizures
pinealectomy
depression
melatonin
MT receptors
Online Access:http://www.mdpi.com/1422-0067/19/7/1973

Internet

http://www.mdpi.com/1422-0067/19/7/1973

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